Glyko® InstantPC™ CHO mAb N-Linked Glycan Library [GKPC-020]

Price:
$ 385.00

Description

The Glyko® InstantPC™ CHO mAb N-Linked Glycan Library consists of complex biantennary oligosaccharides present in many CHO-derived therapeutic glycoproteins. The reducing termini are derivatized with the fluorescent dye, InstantPC.

Please contact us for a representative Certificate of Analysis.

Size: ~25 injections

Product Code: GKPC-020

Structures

Below is a table indicating the N-glycans typically contained in this library. Due to variability in starting material, actual glycans identified in each lot may be subject to change. If you would like more information about our current lot(s), please contact us.

Table 1 - N-Glycans InstantPC CHO mAb N-Linked Glycan Library (GKPC-020)

Glycan Identification

ProZyme

Common

Oxford (New) [1]

Structure [2]

Asialo-, agalacto-, biantennary, -1 N-Acetylglucosamine

NGA2-N

G0-N

A1

Asialo-, agalacto-, biantennary with core fucose, -1 N-Acetylglucosamine

NGA2F-N

G0F-N

F(6)A1

Asialo-, agalacto-, biantennary

NGA2

G0

A2

Asialo-, agalacto-, biantennary with core fucose

NGA2F

G0F

F(6)A2

Oligomannose 5

 

Man-5

Man5

M5

Asialo-, mono-galactosylated, biantennary

NA2G1[6]

G1[6]

A2[6]G(4)1

Asialo-, mono-galactosylated, biantennary with core fucose, -1 N-Acetylglucosamine

NA2G1F-N

G1F-N

F(6)A1G(4)1

Asialo-, mono-galactosylated, biantennary

NA2G1[3]

G1[3]

A2[3]G(4)1

Asialo-, mono-galactosylated, biantennary with core fucose

NA2G1F[6]

G1F[6]

F(6)A2[6]G(4)1

Asialo-, mono-galactosylated, biantennary with core fucose

NA2G1F[3]

G1F[3]

F(6)A2[3]G(4)1

Asialo-, galactosylated biantennary with core fucose

NA2F

G2F

F(6)A2G(4)2

Structure Key [2]:

Structures drawn using GlycoWorkbench [3]. 

  1. GlycoBase 3.2.4. [Internet]. Blackrock, Ireland: National Institute for Bioprocessing Research and Training (NIBRT); c2012. Guide to the abbreviations used to identify 2AB labelled N-glycans; [cited 2016 Apr 19].  Available from: www.glycobase.nibrt.ie/glycobase/documents/abbreviations.pdf
  2. Harvey DJ, Merry AH, Royle L, Campbell MP, Dwek RA, Rudd PM. Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds.  2009 Aug;9(15):3796-801
  3. Ceroni A, Maass K, Geyer H, Geyer R, Dell A, Haslam SM. GlycoWorkbench: a tool for the computer-assisted annotation of mass spectra of glycans.  2008 Apr;7(4):1650-9.

Safety

Product Safety Documentation for GKPC-020:

Product/Part No. Description
GKPC-020 Glyko® InstantPC™ CHO mAb N-Linked Glycan Library