Glyko® A3 (G3S3) [GKC-335300]

Price:
$ 348.00

Description

Glyko® Tri-sialylated-, galactosylated triantennary complex N-glycan (A3)

Qualitative standard for glycan identification.

Alternative glycan names: G3S3, A3G(4)3S3

Monoisotopic mass: 2879.0106

Size: 10 µg, 20 µg (2 x 10 µg)

Product Code: GKC-335300

Structure

Structure drawn in CFG format (1) using GlycoWorkbench (2).  

  • CFG: Functional Glycomics Gateway [Internet]. Symbol and Text Nomenclature for Representation of Glycan Structure. Nomenclature Committee, Consortium for Functional Glycomics; [2012; cited 2015 Oct 6]. Available from: http://glycomics.scripps.edu/CFGnomenclature.pdf
  • Ceroni A, Maass K, Geyer H, Geyer R, Dell A, Haslam SM. GlycoWorkbench: a tool for the computer-assisted annotation of mass spectra of glycans.  2008 Apr;7(4):1650-9.
  • FAQs

    Q. Can I use your unlabeled glycans with dyes that label glycosylamines?

    A. Our unlabeled N-glycan standards have a free reducing end (-OH), so are not suitable for labeling with glycosylamine (-NH2) reactive dyes such as InstantPC, InstantQ and InstantAB.

    We offer a range of InstantDye-labeled glycan standards to support glycoslyamine labels:

    Please contact ProZyme if you would like to request a glycan standard not currently offered.

    Q. What sialic acid linkages are contained within the product?

    A. The product supplied is a mixture of isomers differing in the type of sialic acid linkages: α(2-3) or (2-6). A typical QC chromatogram shows 4 A3 peaks, representing 4 forms of A3 that differ in the way the terminal sialic acid is linked. Our assignments for the peak ID in order of elution: 
    1. 2-3/2-3/2-3 
    2. 2-3/2-3/2-6 
    3. 2-3/2-6/2-6 
    4. 2-6/2-6/2-6 

    Figure 1: Representative HILIC chromatogram of GKC-035300 after labeling with 2-AB.

    Related Products

    See our sialylated library products that contain exclusively α(2-3) or α(2-6)-linked sialic acid:

    α(2-3)-linked sialic acid:

    Sialylated Biantennary N-Glycan Library, labeled with 2-AB or APTS

    Sialylated Triantennary N-Glycan Library, labeled with 2-AB or APTS

    Sialylated Tetraantennary N-Glycan Library, labeled with 2-AB or APTS

    α(2-6)-linked sialic acid:

    α(2-6) Sialylated Biantennary N-Glycan Library, labeled with 2-AB or APTS

    α(2-6) Sialylated Triantennary N-Glycan Library, labeled with 2-AB or APTS

    α(2-6) Sialylated Tetrantennary N-Glycan Library, labeled with 2-AB or APTS

    Safety

    Product Safety Documentation for GKC-335300:

    Product/Part No. Description
    GKC-335300 Glyko® A3 (G3S3)