InstantQ™ CHO mAb N-Linked Glycan Library [GKSQ-020]

Price:
$ 385.00

Description

The Glyko® InstantQ CHO mAb N-Linked Glycan Library consists of complex biantennary oligosaccharides present in many CHO-derived therapeutic glycoproteins. The reducing termini are derivatized with InstantQ dye for analysis on the Gly-Q Glycan Analysis System

Please contact us for a representative Certificate of Analysis.

Product Code: GKSQ-020

Structures

Below is a table indicating the N-glycans typically contained in this library. Due to variability in starting material, actual glycans identified in each lot may be subject to change. If you would like more information about our current lot(s), please contact us.

Table 1 - N-Glycans of InstantQ CHO mAb N-Linked Glycan Library (GKSQ-020)

Glycan Identification

ProZyme

Common

Oxford (New) [1]

Structure [2]

Asialo-, agalacto-, biantennary, -1 N-Acetylglucosamine

NGA2-N

G0-N[3]

A1[3]

Asialo-, agalacto-, biantennary with core fucose, -1 N-Acetylglucosamine

+

Oligomannose 5

NGA2F-N

+

Man-5

G0F-N

+

Man5

F(6)A1

+

M5


Asialo-, agalacto- biantennary

NGA2

G0

A2

Asialo-, agalacto- biantennary with core fucose

NGA2F

G0F

F(6)A2

Asialo-, monogalactosylated biantennary with core fucose, -1 N-Acetylglucosamine

NA2G1F-N

G1F-N[3]

F(6)A1[3]G(4)1

Asialo-, monogalactosylated biantennary

NA2G1

G1[6]

A2[6]G(4)1

Asialo-, monogalactosylated biantennary

NA2G1

G1[3]

A2[3]G(4)1

Asialo-, monogalactosylated biantennary with core fucose

NA2G1F

G1F[6]

F(6)A2[6]G(4)1

Asialo-, monogalactosylated biantennary with core fucose

NA2G1F

G1F[3]

F(6)A2[3]G(4)1

Asialo-, galactosylated biantennary with core fucose

NA2F

G2F

F(6)A2G(4)2

 
Structure Key [2]:

Structures drawn using GlycoWorkbench [3]. 

  1. GlycoBase 3.2.4. [Internet]. Blackrock, Ireland: National Institute for Bioprocessing Research and Training (NIBRT); c2012. Guide to the abbreviations used to identify 2AB labelled N-glycans; [cited 2016 Apr 19].  Available from: www.glycobase.nibrt.ie/glycobase/documents/abbreviations.pdf
  2. Harvey DJ, Merry AH, Royle L, Campbell MP, Dwek RA, Rudd PM. Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds.  2009 Aug;9(15):3796-801
  3. Ceroni A, Maass K, Geyer H, Geyer R, Dell A, Haslam SM. GlycoWorkbench: a tool for the computer-assisted annotation of mass spectra of glycans.  2008 Apr;7(4):1650-9.

Safety

Product Safety Documentation for GKSQ-005:

Product/Part No. Description
GKSQ-020 InstantQ CHO mAb N-Linked Glycan Library