Several of us from ProZyme are attending the annual ASMS conference this week in Atlanta, GA. As always, it's a great opportunity to learn about the latest advances in the mass spec field, particularly as it relates to glycan analysis, and to interact with its practitioners in academia and industry.
We're also pleased to be interacting with Agilent at this conference as part of our campaign to advance glycosciences, together.
Today (Wednesday), John Yan presents poster 228 in the Clinical Analysis III session, on behalf of our collaborator Sarah Totten of Stanford University School of Medicine. The poster, "Quantitative N-Glycan Profiling of Clinical Tissue Samples by On-Line Fluorescence-MS Using a Rapid Labeling Tag", is a collaboration led by the Canary Center at Stanford for Early Cancer Detection. The work examines proteins extracted from prostate cancer tissue, and utilizes Gly-X with InstantPC sample preparation to obtain the released N-glycan profile from glycopeptides in conjunction with Agilent 1260 LC and Agilent 6230 TOF systems.
On Thursday, Aled Jones will present poster 697, "Streamlined Workflows for N-Glycan Analysis of Biotherapuetics Using InstantPC and 2-AB with LC-FLD-MS" as part of the Proteins: PTMs II session. The poster examines the released N-glycan profiles obtained for rituximab (mAb) and etanercept (Fc fusion) using our Gly-X InstantPC and 2-AB Express kits, with separation on Agilent 1290 Infinity II UHPLC and AdvanceBIo Glycan Mapping columns. Fluorescence and mass spec detection of labeled N-glycans are with the Agilent 1260 Infinity II FLD and Agilent 6545 LC/QTOF MS, respectively.
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