Glyko® InstantAB™ Human IgG N-Linked Glycan Library [GKIB-005]

Price:
$ 315.00

Description

Glyko® InstantAB™-(Human IgG N-Linked Glycan Library) 

The Glyko® InstantAB™ Human IgG N-Linked Glycan Library consists of complex biantennary oligosaccharides consistent with N-glycans on normal human IgG. The reducing termini are derivatized with the fluorescent dye, InstantAB.

Please contact us for a representative Certificate of Analysis.

Size: 70 pmol

Product Code: GKIB-005

Structures

Below is a table indicating the N-glycans typically contained in this library. Due to variability in starting material, actual glycans identified in each lot may be subject to change. If you would like more information about our current lot(s), please contact us.

N-Glycans of Human IgG N-Linked Glycan Library (GKIB-005)

Glycan Identification ProZyme Common Oxford (New) [1] Structure [2]
Asialo-, agalacto- biantennary with core fucose NGA2F G0F F(6)A2
Asialo-, agalacto- biantennary with core fucose and with bisecting N-Acetylglucosamine NGA2FB G0FB F(6)A2B
Asialo-, mono-galacto- biantennary NA2G1 G1 A2G1
Asialo-, monogalactosylated biantennary with core fucose NA2G1F G1F F(6)A2G1
Asialo, mono-galactosylated biantennary, core substituted with fucose and bisecting N-Acetylglucosamine NA2G1FB G1FB F(6)A2BG(4)1
Asialo, galactosylated biantennary NA2 G2 A2G(4)2
Asialo, galactosylated biantennary with core fucose NA2F G2F F(6)A2G(4)2
Asialo, galactosylated biantennary with core fucose and bisecting N-Acetylglucosamine NA2FB G2FB F(6)A2BG(4)2
Mono-sialylated, mono-galactosylated biantennary with core fucose NA2G1FS1 G1FS1 F(6)A2G(4)1S(6)1
Mono-sialylated, galactosylated biantennary A1 G2S1 A2G(4)2S(6)1
Mono-sialylated, galactosylated biantennary with core fucose A1F G2FS1 F(6)A2G(4)2S(6)1
Mono-sialylated, galactosylated biantennary with core fucose and bisecting N-Acetylglucosamine A1FB G2FBS1 F(6)A2BG(4)2S(6)1
Di-sialylated, galactosylated biantennary A2 G2S2 A2G(4)2S(6)2
Di-sialylated, galactosylated biantennary with core fucose A2F G2FS2 F(6)A2G(4)2S(6)2
Di-sialylated, glactosylated biantennary with core fucose and bisecting N-Acetylglucosamine A2FB G2FBS2 F(6)A2BG(4)2S(6)2

Structure Key [2]:

Structures drawn using GlycoWorkbench [3]. 

  1. GlycoBase 3.2.4. [Internet]. Blackrock, Ireland: National Institute for Bioprocessing Research and Training (NIBRT); c2012. Guide to the abbreviations used to identify 2AB labelled N-glycans; [cited 2016 Apr 19].  Available from: www.glycobase.nibrt.ie/glycobase/documents/abbreviations.pdf
  2. Harvey DJ, Merry AH, Royle L, Campbell MP, Dwek RA, Rudd PM. Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds.  2009 Aug;9(15):3796-801
  3. Ceroni A, Maass K, Geyer H, Geyer R, Dell A, Haslam SM. GlycoWorkbench: a tool for the computer-assisted annotation of mass spectra of glycans.  2008 Apr;7(4):1650-9.

Safety

Product Safety Documentation for GKIB-005:

Product/Part No. Description
GKIB-005 Glyko® InstantAB™ Human IgG N-Linked Glycan Library 

 


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